Eastern Equine Encephalitis (EEE) IgM Antibody

WSLH Department: CDD - Communicable Disease Division
WSLH Test Code: SS02291
Availability: Test is performed weekly
Turn-around Time: 2-8 days
Recommended Uses: Serodiagnosis of a recent infection with EEE in individuals with symptoms of arbovirus infection.
Contraindications: Testing will not be performed as a screening test or on patients without symptoms of EEE infection.
Additional Tests Performed:
Patient Preparations:
Specimen Requirements: 1-3 ml serum or 8.5 ml SST vacutainer tube, no additives; CSF, minimum 200 µl. CSF must be accompanied by serum specimen
Specimen Handling & Transport: Specimens should be stored at 2-8 degrees C, transported with a frozen cool pack, and should be received within 48 hours of collection. If specimens will not be tested for 3 or more days, they should be frozen at -20°C until ready for shipment and shipped on dry ice.
Collection Kit/Container: Serology Specimens
Sterile Transfer Tube
Collection Instructions:
Unacceptable Conditions:
Requisition Form: CDD Requisition Form B
Required Information: Clinical information regarding symptoms and onset must be provided. Laboratory regulations require the following minimum information to be provided on the requisition form for a specimen to be accepted for testing: Patient name or unique identifier; date and time of collection, patient date of birth and sex, specimen type/site of collection, test request(s), clinician name and UPIN, and address for reporting results. Please be certain that name/identifier on the form matches that on the specimen label.
Results Include: Negative, Presumptive Positive or Nonspecific.
Limitations: Cross-reaction may occur between arboviruses. Negative results on a single acute phase specimen do not rule out infection, as specimen may have been obtained prior to the development of an antibody response.
Additional Tests Recommended: Enterovirus PCR, HSV, or other individual arboviral agents (LAC, WNV, POW, SLE) are also recommended.
Additional Comments: The MIA test methodology was developed at the CDC and validated at WSLH. It has not been cleared or approved by the U.S. Food and Drug Administration. Testing is performed weekly. Please contact the laboratory for information about out-of-season arbovirus testing. Presumptive positives are sent to CDC for confirmatory testing.
Methodology: Microsphere Immunoassay (MIA)
Includes: Qualitative IgM testing for Eastern Equine Encephalitis.
CPT Code: 86652
Price: $88.00
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