Mumps IgM and IgG Antibody Print

WSLH Department: CDD - Communicable Disease Division
WSLH Test Code: SS02130
Availability: Weekdays
Turn-around Time: 1-3 days for IgG; approximately 2 weeks for IgM
Recommended Uses: Early diagnosis of mumps infection
Additional Tests Performed:
Patient Preparations: Acute serum collected 1-7 days after an acute onset of unilateral or bilateral tender swelling of the parotid or salivary gland.
Specimen Requirements: Minimum of 0.5 ml serum.
Specimen Handling & Transport: Store refrigerated at 2-8C, and freeze within 48 hours of collection. Transport on dry ice.
Collection Kit/Container: Serology Specimens
Sterile Transfer Tube
Collection Instructions: Routine blood draw
Unacceptable Conditions: Obvious microbial contamination and lipemic specimens
Requisition Form: CDD Requisition Form B
Required Information: Laboratory regulations require the following minimum information to be provided on the requisition form for a specimen to be accepted for testing: Patient name or unique identifier; date and time of collection, patient date of birth and sex, specimen type/site of collection, test request(s), clinician name and UPIN, and address for reporting results. Please be certain that name/identifier on the form matches that on the specimen label.
Results Include: Mumps IgG interpretation; Mumps IgM EIA index and interpretation
Limitations: The presence of mumps IgM is indicative of a recent exposure, but cannot differentiate between primary infection and vaccination. Mumps infection can occur without parotitis. The absence of IgM and IgG may indicate that the specimen was collected too early in the course of infection.
Additional Tests Recommended: Mumps Virus PCR (VR01714), Influenza testing
Additional Comments: Specimens must be frozen within 48 hours of collection or they will be rejected by CDC. Please take this timeframe into consideration when transporting to WSLH. IgM absent, IgG present indicates patient is not currently infected with mumps. Detectable levels of IgG antibody may indicate the patient has been exposed through past infection or vaccination. Testing for other viral/bacterial causes of parotid swelling (enteroviruses, Herpes simplex, herpes zoster, influenza A, adenovirus, parainfluenza, and S. aureus) should also be considered. Presence of IgM is presumptive evidence of a recent or current infection. IgM equivocal result does not rule out or confirm a recent or current infection. The absence of IgM and IgG does not rule out mumps, and may indicate patient susceptibility to mumps infection.
Methodology: Mumps IgG Indirect Fluorescent Antibody (IFA) performed at WSLH: Mumps IgM EIA performed at CDC
Includes: Qualitative assay for the detection of IgM and IgG antibodies to Mumps virus.
CPT Code: 86735
Price: $97.00
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