Histology - Tissue Biopsy

WSLH Department: Cytology
WSLH Test Code: 92003 TBX
Availability: Monday - Friday
Turn-around Time: 7-10 business days
Recommended Uses: Evaluation for premalignant, malignant, inflammatory and infectious lesions.
Contraindications: Bleeding risk as determined by the collecting clinician.
Additional Tests Performed:
Patient Preparations: Dependent on site of specimen, patient, and clinician. For female genital tract biopsies: have patient empty bladder and bowel prior to procedure. Instruct patient to not douche, use vaginal products, or have sexual intercourse 24 hours prior to biopsy.
Specimen Requirements: Small and medium biopsies, curettings; in container with 10% neutral buffered formalin
Specimen Handling & Transport: Place tightened container in a biohazard bag. Complete request form and place both into Styrofoam mailer. Label mailer with clinic address and WSLH address. Place biohazard sticker on mailer. Send to WSLH via courier or shipping carrier with a tracking option strongly preferred.
Collection Kit/Container: Call 1-800-862-1088 for specific kit supplies.
Collection Instructions: Collect sample using biopsy forceps or curetting tool, LEEP, or LOOP. Place specimen sample into vial containing 10% neutral buffered formalin. Container must be labeled with patient's full legal name, date of collection, specimen source, and name of clinician authorized to order the test.
Unacceptable Conditions: Unlabeled specimens and improperly fixed specimens will not be evaluated.
Requisition Form: Histology
Required Information: Clinician must include pertinent clinical history, appropriate ICD10 code and payor information. Patient name and unique identifier; date and time of collection; patient date of birth; and sex; specimen type/site of collection; test; orders; clinician name; phone; and NPI; and clinic address for reporting results.
Results Include: Benign Cervical Mucosa Without Evidence of Malignancy, Low grade squamous intraepithelial lesion (LSIL, cervical intraepithelial neoplasia 1, CIN1, mild dysplasia), High grade squamous intraepithelial lesion (HSIL, cervical intraepithelial neoplasia 2, CIN2, moderate dysplasia), High grade squamous intraepithelial lesion (HSIL, cervical intraepithelial neoplasia 3, CIN3, carcinoma in situ or severe dysplasia), Endocervical Adenocarcinoma In Situ, and Positive for Malignancy. In vaginal/vulvar specimens CIN grade is replaced with VAIN or VIN respectively. Results may also include inflammatory, bacterial and viral findings, or other histological diagnoses in accord with Rosai and Ackerman's Surgical Pathology, 11th Edition.)
Limitations: As with any laboratory test, both false negative and false positive results may occur. Findings must be correlated with history and other test results.
Additional Tests Recommended:
Additional Comments: Immunohistochemistry may be ordered at the discretion of the pathologist to further confirm or rule out differential diagnoses (CPT 88342 and price $86.00).
Methodology: Histologic evaluation of tissue biopsies from a variety of body sites.
Includes: Small and medium sized biopsies from the genital tract and other sites.
CPT Code: 88305
Price: $115.00
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