Newborn Screening Panel
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| WSLH Department: | Newborn Screening Laboratory |
| WSLH Test Code: | NB28100 |
| Day(s) Performed: | Monday - Saturday |
| Turn-around Time: | 48-72 hours for screening negative (normal) results; Screening positive (abnormal) results are communicated to health care provider as soon as they are available |
| Recommended Uses: | Screen babies for listed congenital disorders |
| Contraindications: | |
| Additional Tests Performed: |
| Patient Preparations: | See back of collection card (213), and the newborn screening website: http://www.slh.wisc.edu/clinical/newborn/health-care-professionals-guide/how-to-collect-a-blood-specimen/when-to-collect-a-blood-specimen-2/ |
| Specimen Requirements: | Whole blood spotted on filter paper. The filter paper is part of the collection kit. |
| Specimen Handling & Transport: | Dry card horizontally for a minimum of 3 hrs. Dried specimens should be transported to State Laboratory of Hygiene within 24 hours of specimen collection (the State Laboratory of Hygiene provides a next-day courier delivery service). |
| Collection Kit/Container: |
213-Newborn Screening Blood Collection Card
|
| Collection Instructions: | Specimens should be collected within 24-48 hours after birth. For extended hospitalizations, follow the recommendations posted on the newborn screening website: http://www.slh.wisc.edu/clinical/newborn/health-care-professionals-guide/how-to-collect-a-blood-specimen/when-to-collect-a-blood-specimen-2/ |
| Unacceptable Conditions: | Newborn screening specimens are deemed unsatisfactory for testing for the following reasons: Blood clots; Layered blood; Incomplete saturation; Plasma separation for red blood cells; Contamination of filter paper; Damage to filter paper; Blood on tan cover; Delay in transit more than seven days. |
| Requisition Form: |
Attached to blood collection card
|
| Required Information: | Each data field on the requisition form (http://www.slh.wisc.edu/clinical/newborn/health-care-professionals-guide/how-to-collect-a-blood-specimen/how-to-complete-the-blood-collection-form/) |
| Results Include: | A recommendation for follow-up action, if necessary |
| Limitations: | Test results may be compromised if: Specimen is collected prior to 24 hours after birth; Specimen is collected after baby has received a blood transfusion; Specimen is collected while baby is receiving total parenteral nutrition |
| Additional Tests Recommended: | Confirmatory testing or a repeat newborn screen may be recommended, depending on test results. |
| Additional Comments: |
| Methodology: | Enzymatic assay, immunoreaction assay, electrophoresis, high performance liquid chromography, tandem mass spectrometry, polymerase chain reaction (PCR), real-time PCR, digital droplet PCR, and sequencing technology |
| Includes: | Screen for the following disorders: arginosuccinic acidemia, biotinidase deficiency, citrullinemia (I & II), congenital adrenal hyperplasia, congenital hypothyroidism, cystic fibrosis, fatty acid oxidation disorders (12), galactosemia, sickle cell disease, hemoglobin S-Beta thalessemia, hemoglobin S-C disease, hemoglobin E-Beta thalessemia, Beta thalassemia, homocystinuria, hypermethioninemia, maple syrup disease, organic acidemia (12), phenylketonuria (PKU), hyperphenylalaninemia, tyrosinemia (I, II & III), severe combined immune deficiency (SCID), and spinal muscular atrophy (SMA), and Pompe disease. |
| CPT Code: | S3620 |
| Price: | $195.00 effective 7/11/23 |