Mycobacterium avium complex (MAC) Susceptibility
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| WSLH Department: | CDD - Communicable Disease Division |
| WSLH Test Code: | MM00202 |
| Day(s) Performed: | Test is run weekly |
| Turn-around Time: | 2-3 weeks |
| Recommended Uses: | Clarithromycin testing should be performed on isolates from blood or tissue (disseminated disease) and clinically significant respiratory specimens from patients who have failed prior macrolide therapy or prophylaxis. (MAC strains not previously exposed to macrolide therapy or prophylaxis are uniformly susceptible to the macrolides.) |
| Pre-approval: | No |
| Contraindications: | |
| Additional Tests Performed: |
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| Preparation for Collection: | |
| Specimen Requirements: | M. avium complex isolate in broth or solid media; pure culture is required for testing. |
| Collection Instructions: | |
| Collection Kit/Container: |
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| Requisition Form: |
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| Required Information: | Laboratory regulations require the following minimum information to be provided on the requisition form for a specimen to be accepted for testing: Patient name or unique identifier, date and time of collection, patient date of birth and sex, specimen type/site of collection, test request(s), clinician name and UPIN, and address for reporting results. Please be certain that name/identifier on the form matches that on the specimen label which is required to have a minimum of two identifiers. |
| Rejection Criteria: | |
| Specimen Handling: | Cultures may be transported to the laboratory at ambient temperatures. Avoid temperature extremes during transport. |
| Packaging Requirements: | |
| Courier Information: | Contact Purple Mountain Dispatch at 800-990-9668 for specimen pickup |
| Specimen Receiving Hours: | Monday-Friday 6:00 AM - 4:30 PM, Saturday 6:30 AM - 12:30 PM |
| Results Include: | Numeric MIC result and interpretation as Susceptible, Intermediate or Resistant using criteria established by the Clinical and Laboratory Standards Institute (CLSI). |
| Limitations: | Mixed or contaminated cultures will take longer and prevent testing. |
| Additional Tests Recommended: | |
| Additional Comments: |
| Methodology: | Broth microdilution |
| Includes: | Clarithromycin Minimum Inhibitory Concentration (MIC) susceptibility testing |
| Regulatory Compliance: |
| CPT Code: | 87186 |
| Price: | $166.00 |
| Fee Exempt Eligible: | No |
| Billing and Revenue Office: | 1-800-862-1065 arbill@slh.wisc.edu |