Syphilis TP-PA !!! NOTE: The contents are valid only for: 07/20/2024 !!!

WSLH Department: CDD - Communicable Disease Division
WSLH Test Code: SS02013
Availability: Test is run 2 times weekly (Tuesdays and Fridays).
Turn-around Time: 1-5 days
Recommended Uses: To confirm the reactive results of a nontreponemal screening test for syphilis (VDRL, RPR) or as a diagnostic test in patients with a nonreactive nontreponemal test but with signs or symptoms suggestive of late syphilis.
Contraindications: A reactive TP-PA test will remain reactive for life even with successful treatment and therefore is not useful in post-treatment evaluation.
Additional Tests Performed:
Patient Preparations: Routine blood draw
Specimen Requirements: 1-3 ml serum
Specimen Handling & Transport: Specimens must be stored refrigerated (2-8C) and transported with frozen cool packs.
Collection Kit/Container: Serology Specimens
Sterile Transfer Tube
Collection Instructions: Routine blood draw
Unacceptable Conditions:
Requisition Form: CDD Requisition Form B
Required Information: Laboratory regulations require the following minimum information to be provided on the requisition form for a specimen to be accepted for testing: Patient name or unique identifier; date and time of collection, patient date of birth and sex, specimen type/site of collection, test request(s), clinician name and UPIN, and address for reporting results. Please be certain that name/identifier on the form matches that on the specimen label.
Results Include: Non-Reactive: Suggests that a reactive nontreponemal test result (VDRL or RPR) is a false-positive reaction. False-positive nontreponemal results are seen in certain acute and chronic infections, following immunizations, in autoimmune diseases, and in intravenous drug addiction.

Reactive: Confirms the reactivity of a nontreponemal test (VDRL or RPR) used as the screening test for syphilis. A reactive TP-PA result suggests current or past infection with pathogenic treponemes, and may also support the diagnosis of late syphilis or long-standing late latent syphilis in the small proportion of cases in which the nontreponemal test has become non-reactive, but infection is suspected because of the clinical presentation or a history consistent with syphilis infection.

Inconclusive: May indicate that the patient is beginning to produce anti-treponemal antibodies due to recent infection. Submission of another specimen in 2 weeks to detect seroconversion is recommended.
Limitations: The TP-PA test may be reactive in persons from areas where yaws or pinta was, or is, endemic. Interpretaton of results of TP-PA must be used in conjunction with the clinical symptoms, medical history and other clinical laboratory findings to produce an overall clinical diagnosis. A reactive TP-PA test will remain reactive following treponemal infection; it should not be used to evaluate response to therapy.
Additional Tests Recommended: A repeated inconclusive specimen may be tested by other methods such as FTA-ABS.
Additional Comments:
Methodology: Particle agglutination TP-PA
Includes: Qualitative gelatin particle agglutination test for Treponema pallidum antibody.
CPT Code: 86780
Price: $44.00
!!! NOTE: The contents are valid only for: 07/20/2024 !!!